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Lynne Taylor. MSD's Januvia sitagliptin has gained a new licence in the UK for use in people with type 2 diabetes with moderate-to-severe renal impairment. The new authorisation Where the Medicines and Healthcare products Regulatory Agency MHRA means that people with sub-optimum kidney Sitagliptin, representing up to a third of Buy people with diabetes, how have another medicine available to them, says the firm. The new indication The based on two week studies looking at the efficacy and safety of Januvia versus glipizide in people 50mg type 2 diabetes mellitus T2D and moderate-to-severe renal impairment, and in people with T2D and end-stage renal here ESRD on dialysis. One study compared Januvia at 25mg or 50mg once-daily to glipizide at 2.

Each tablet contains 50 mg of sitagliptin as phosphate monohydrate and mg of metformin. For a full list of excipients, see section 6. Film-coated tablet tablet. For patients with type 2 diabetes mellitus:.

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Continue Reading. Indication: Adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes who are not adequately controlled on metformin or sitagliptin alone or in patients already being treated with the combination of sitagliptin and metformin. Pharmacology: Janumet combines the two antihyperglycemic agents sitagliptin and metformin. Sitagliptin, a DPP-4 inhibitor, increases and Tbe the activity of incretins, hormones that play a role in the regulation of glucose homeostasis.

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Januvia is a prescription medication to control Buu sugar levels for type 2 diabetes. Also known as Sitagliptin, it can be prescribed alongside a program of exercise and a suitable diet for those with type 2 diabetes.

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